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While PXE services don't tend to have many issues, you may occasionally run into issues with PXE reps.
Issues seen at Tufts
With some PXE reps, you may get errors when attempting to PXE boot from them. While there can be a variety of causes (detailed here, this is generally fixed by disabling some of the F8 options on the PXE rep. Additional instrucions can be found here: http://community.landesk.com/support/docs/DOC-22479
Generic issues
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Enable logging for Landesk PXE service
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If you are having issues, it may be worthwhile to enable logging to help track the issue.
In order to enable logging change the registry key “PxeMtftp_DebugOutToFile_On” under HKLM\Software\INTEL\PXE on the PXE rep to "1". Then, either restrat the computer or the Landesk PXE MTFTP Service. The Log file pxemtftp.log can be found in c:\program files\LANDesk\PXE\System
http://community.landesk.com/support/docs/DOC-11704
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Troubleshooting PXE
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Landesk has a very detailed article with a collection of PXE errors and troubleshotting steps. The article can be found here: http://community.landesk.com/support/docs/DOC-8358